Prof. Ronald Melki is co-organizer of Protein phase transitions in aging and age-related diseases conference
PD-MitoQUANT PI Prof. Dr Ronald Melki, CNRS, Fontenay-aux-Roses, France is the co-organizer of the Protein phase transitions in aging and age-related diseases: from atomic resolution to cellular solutions conference which will take place in Roscoff, Brittany, France from October 17th through the 21st, 2022. The deadline for applications is June 13th; click here for application guidelines. Invited speakers include PI Dr Olga Corti, ICM, who will speak about Mitochondrial quality control in Parkinson's disease and Ronald Melki, CNRS: Fibril polymorphisms and propagation About this meeting: Cells and organisms maintain protein homeostasis in several cooperating ways, which include protein folding, degradation, and sequestration. During aging, the ability to maintain protein homeostasis declines, which leads to the accumulation of aggregation-prone proteins. These aggregation-prone proteins can accelerate aging and cause age-related diseases like Parkinson's disease, tauopathies, Alzheimer's, and Amyotrophic Lateral Sclerosis. How they do so is still not fully understood. Understanding the underlying mechanisms will be important for the development [...]
Missed the Parkinson’s Research in Ireland event? Videos are now available!
The third annual Parkinson's Research in Ireland talk series was held on March 31st and April 7th, 2022. Videos of the short talk are now available for viewing. Dr Niamh Connolly, the Deputy PD-MitoQUANT Coordinator based at the Royal College of Surgeons in Ireland, spoke about results from the project to characterise mitochondrial dysfunction in Parkinson’s. https://vimeo.com/695823375 Richard Campbell of Parkinson’s UK spoke about his role as a Person with Parkinson’s in the PD-MitoQUANT project and his wider work in Public Patient Involvement. https://vimeo.com/695822475 Lewis Killin of SYNAPSE Research Management Partners spoke about the IMI2-funded Neuronet project (https://www.imi-neuronet.org/) and the role of public-private partnerships in research for neurodegenerative diseases. https://vimeo.com/697443977 Roisin Vance of Beaumont Hospital spoke about her role as a physiotherapist, focusing on physiotherapy for Parkinson’s. https://vimeo.com/697389078 Once again, we wish to thank all speakers and organisers from the Royal College of Surgeons in Ireland and Pintail Limited.
Publication news from Dr Daniele Bano and team at the DZNE
Congratulations to PI Dr Daniele Bano, Joshua Jackson, Lena Wischhof, Enzo Scifo, Anna Pellizzer, Yiru Wang, Antonia Piazzesi, DeboraGentile, Sana Siddig, Miriam Stork, Chris E. Hopkins, KristianHändler, Joachim Weis, Andreas Roos, Joachim L. Schultze, Pierluigi Nicotera, Dan Ehninger, and the team of researchers at the DZNE for their recent paper in Molecular Metabolism. The open-access study titled 'SGPL1 stimulates VPS39 recruitment to the mitochondria in MICU1 deficient cells' was published on April 19th, 2022. DOI: https://doi.org/10.1016/j.molmet.2022.101503 Download the pdf here.
PD-MitoQUANT research will be presented at FENS
Two PD-MitoQUANT research abstracts have been accepted for presentation at the 13th FENS Forum of Neuroscience to be held in Paris, France on the 9th through the 13th of July 2022. The first will be presented by our partners at the Institut de Cerveau (ICM) and is entitled "Cultured mouse dopaminergic neurons as a model system to study alpha-Synuclein aggregation and neurodegeneration in Parkinson’s disease" by researchers and is the work of Patrick Pierre Michel, Aurore Tourville, David Akbar, Olga Corti, Jochen H M Prehn, Ronald Melki, and Stephane Hunot. The second is "Systems modelling of mitochondrial bioenergetics to explore molecular defects contributing to pathogenesis in Parkinson’s" and will be presented by the Royal College of Surgeons in Ireland researchers Niamh Connolly and Sandeep Chenna. This poster represents the work of Sandeep Chenna, Ronald Melki, Tina Charlotte Stummann, Karina Fog, Katarina Willen, Orla Watters, Marko Kostic, Franziska Walter, Heiko Dussmann [...]
DZNE Prof. DiMonte’s PD-MitoQUANT study published in Brain Communications
Congratulations to the research team of Céline Galvagnion, Frederik Ravnkilde Marlet, Silvia Cerri, Anthony H V Schapira, Fabio Blandini, Donato A Di Monte (DZNE). Their paper entitled Sphingolipid changes in Parkinson L444P GBA mutation fibroblasts promote α-synuclein aggregation was published in Brain Communications on April 1st, 2022. DOI: https://doi.org/10.1093/brain/awab371 Citation: Céline Galvagnion, Frederik Ravnkilde Marlet, Silvia Cerri, Anthony H V Schapira, Fabio Blandini, Donato A Di Monte, Sphingolipid changes in Parkinson L444P GBA mutation fibroblasts promote α-synuclein aggregation, Brain, 2022;, awab371, https://doi.org/10.1093/brain/awab371 Find this with all other PD-MitoQUANT publications here.